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The antibody against MYB was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 380-640 of human MYB (NP_005366.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against MYB was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 380-640 of human MYB (NP_005366.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10275A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYB |
| Target Synonyms | efg; Cmyb; c-myb; c-myb_CDS; MYB | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat | Application | ELISA, WB |
| Immunogen Description | A synthetic peptide corresponding to a sequence within amino acids 380-640 of human MYB (NP_005366.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P10242 | Immunogen Sequence |
Uniprot Id
P10242
Target Species
Human
Target Name
MYB
Target Full Name
Transcriptional activator Myb
Target Function
Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Target Subcellular Location
Nucleus.
Target Synonyms
C myb; c myb protein (140 AA); c-myb protein (140 AA); c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; Cmyb; efg; Myb; MYB proto-oncogene transcription factor; MYB_HUMAN; ONCOGENE AMV; Oncogene MYB; Proto oncogene c Myb; Proto-oncogene c-Myb; Transcriptional activator Myb; v myb avian myeloblastosis viral oncogene homolog; v-myb avian myeloblastosis viral oncogene homolog
Target Background
This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.
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