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Rabbit anti-Human MYB Polyclonal Antibody

The antibody against MYB was raised in rabbit using the Synthesized non-phosphopeptide derived from Human Myb around the phosphorylation site of serine 532 (V-E-S(p)-P-T). as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-42495A

The antibody against MYB was raised in rabbit using the Synthesized non-phosphopeptide derived from Human Myb around the phosphorylation site of serine 532 (V-E-S(p)-P-T). as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-42495A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYB
FormLiquidSpecies ReactivityHuman, Mouse
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized non-phosphopeptide derived from Human Myb around the phosphorylation site of serine 532 (V-E-S(p)-P-T).Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP10242
Background Information
  • Uniprot Id

    P10242

  • Target Species

    Human

  • Target Name

    MYB

  • Target Full Name

    Transcriptional activator Myb

  • Target Function

    Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    C myb; c myb protein (140 AA); c-myb protein (140 AA); c-myb_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; c-myb8B_CDS; Cmyb; efg; Myb; MYB proto-oncogene transcription factor; MYB_HUMAN; ONCOGENE AMV; Oncogene MYB; Proto oncogene c Myb; Proto-oncogene c-Myb; Transcriptional activator Myb; v myb avian myeloblastosis viral oncogene homolog; v-myb avian myeloblastosis viral oncogene homolog

  • Target Background

    This gene encodes a protein with three HTH DNA-binding domains that functions as a transcription regulator. This protein plays an essential role in the regulation of hematopoiesis. This gene may be aberrently expressed or rearranged or undergo translocation in leukemias and lymphomas, and is considered to be an oncogene. Alternative splicing results in multiple transcript variants.

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