Rabbit anti-Human MYBL1 Polyclonal Antibody

The antibody against MYBL1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 443-692 of human MYBL1 (NP_001138227.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-08910A

Number

Cat.No	ADA-08910A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	MYBL1
Target Synonyms	AMYB; A-MYB; MYBL1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, MCF7	Application	ELISA, WB

Cat.No

ADA-08910A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

MYBL1

Target Synonyms

AMYB; A-MYB; MYBL1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, MCF7

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 443-692 of human MYBL1 (NP_001138227.1).	Target Species	Human
Uniprot ID	P10243	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 443-692 of human MYBL1 (NP_001138227.1).

Target Species

Human

Uniprot ID

P10243

Immunogen Sequence

Background Information

Uniprot Id

P10243
Target Species

Human
Target Name

MYBL1
Target Full Name

Myb-related protein A
Target Function

Transcription factor that specifically recognizes the sequence 5'-YAAC[GT]G-3'. Acts as a master regulator of male meiosis by promoting expression of piRNAs: activates expression of both piRNA precursor RNAs and expression of protein-coding genes involved in piRNA metabolism. The piRNA metabolic process mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons, which is essential for the germline integrity. Transcriptional activator of SOX30.
Target Subcellular Location

Nucleus.
Target Tissue Specificity

Expressed in a variety of lymphoid and solid tumor lines cultured in vitro.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

A-Myb; AMYB; MGC120059; MGC120061; Myb related protein A; Myb-like protein 1; Myb-related protein A; MYBA_HUMAN; MYBL1
Target Background

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.

Rabbit anti-Human MYBL1 Polyclonal Antibody

Specifications

Immunogen Information

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