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The antibody against MYH7B was raised in rabbit using the Recombinant Human Myosin-7B protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against MYH7B was raised in rabbit using the Recombinant Human Myosin-7B protein (1-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using MYH7B Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using MYH7B Antibody at dilution of 1:1002
| Cat.No | ADC-24306A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYH7B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Myosin-7B protein (1-176AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A7E2Y1 |
Uniprot Id
A7E2Y1
Target Species
Human
Target Name
MYH7B
Target Full Name
Myosin-7B
Target Function
Involved in muscle contraction.
Target Subcellular Location
Membrane; Peripheral membrane protein.
Target Protein Families
TRAFAC class myosin-kinesin ATPase superfamily, Myosin family
Target Tissue Specificity
Expressed in heart, skeletal muscle, testis, and all specific brain regions examined. Slightly lower expression was detected in ovary and kidney, and intermediate expression was detected in lung, pancreas, spleen and liver.
Target Synonyms
Antigen MLAA-21; cardiac muscle beta isoform; Myh7b; MYH7B_HUMAN; Myosin cardiac muscle beta chain; Myosin heavy chain 7B; Myosin-7B; Slow A MYH14
Target Background
The myosin II molecule is a multi-subunit complex consisting of two heavy chains and four light chains. This gene encodes a heavy chain of myosin II, which is a member of the motor-domain superfamily. The heavy chain includes a globular motor domain, which catalyzes ATP hydrolysis and interacts with actin, and a tail domain in which heptad repeat sequences promote dimerization by interacting to form a rod-like alpha-helical coiled coil. This heavy chain subunit is a slow-twitch myosin. Alternatively spliced transcript variants have been found, but the full-length nature of these variants is not determined.
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