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Rabbit anti-Human MYL9 Polyclonal Antibody

The antibody against MYL9 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYL9 (NP_006088.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-11263A

The antibody against MYL9 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYL9 (NP_006088.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

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Specifications


Cat.No ADA-11263A ClonalityPolyclonal
Host SpeciesRabbitTarget NameMYL9
Target SynonymsLC20; MLC2; MRLC1; MYRL2; MLC-2C; MMIHS4; MYL9FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesC6, Rat heart, C2C12, Mouse lungApplicationELISA, WB, IF/ICC

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human MYL9 (NP_006088.2).Target SpeciesHuman
Immunogen SequenceMSSKRAKAKTTKKRPQRATSNVFAMFDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEAPGPINFTMFLTMFGEKLNGTDPEUniprot IDP24844
Background Information
  • Uniprot Id

    P24844

  • Target Species

    Human

  • Target Name

    MYL9

  • Target Full Name

    Myosin regulatory light polypeptide 9

  • Target Function

    Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion. In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.

  • Target Tissue Specificity

    Smooth muscle tissues and in some, but not all, nonmuscle cells.

  • Target Research Area

    Cancer

  • Target Synonyms

    20 kDa myosin light chain; Human 20kDa myosin light chain (MLC2) mRNA complete cds; LC20; MGC3505 ; MLC 2 ; MLC-2C; MLC2 ; MLY 9; MRLC1 ; MYL9; MYL9_HUMAN; Myosin light chain 9 regulatory; Myosin light polypeptide 9 regulatory; myosin regulatory light chain 1; Myosin regulatory light chain 2; Myosin regulatory light chain 2 smooth muscle isoform; Myosin regulatory light chain 9; Myosin regulatory light chain MRLC1; Myosin regulatory light polypeptide 9; Myosin RLC; Myosin vascular smooth muscle light chain 2; MYRL2 ; OTTHUMP00000030857; smooth muscle isoform

  • Target Background

    Myosin, a structural component of muscle, consists of two heavy chains and four light chains. The protein encoded by this gene is a myosin light chain that may regulate muscle contraction by modulating the ATPase activity of myosin heads. The encoded protein binds calcium and is activated by myosin light chain kinase. Two transcript variants encoding different isoforms have been found for this gene.

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