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The antibody against MYLK2 was raised in rabbit using the Fusion protein of Human MYLK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against MYLK2 was raised in rabbit using the Fusion protein of Human MYLK2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-31667A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYLK2 |
| Target Synonyms | KMLC antibody; MLCK antibody; MLCK, skeletal/cardiac antibody; Skeletal muscle myosin light chain kinase antibody; Skeletal myosin light chain kinase antibody; skeletal/cardiac muscle antibody; skMLCK antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human MYLK2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H1R3 |
Uniprot Id
Q9H1R3
Target Species
Human
Target Name
MYLK2
Target Full Name
Myosin light chain kinase 2, skeletal/cardiac muscle
Target Function
Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.
Target Involvement
Cardiomyopathy, familial hypertrophic (CMH)
Target Subcellular Location
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Target Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Target Tissue Specificity
Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.
Target Synonyms
KMLC; MLCK; MLCK, skeletal/cardiac; MLCK2; MYLK 2; MYLK2; MYLK2_HUMAN; Myosin light chain kinase 2; Myosin light chain kinase 2 skeletal muscle; Myosin light chain kinase 2 skeletal/cardiac muscle; MYOSIN LIGHT POLYPEPTIDE KINASE; Myosin light polypeptide kinase, skeletal/cardiac; Skeletal muscle myosin light chain kinase; Skeletal myosin light chain kinase; skeletal/cardiac muscle; skMLCK
Target Background
This gene encodes a myosin light chain kinase, a calcium/calmodulin dependent enzyme, that is exclusively expressed in adult skeletal muscle.
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