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The antibody against MYOZ2 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 21-70 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against MYOZ2 was raised in rabbit using the Synthetic peptide from Human protein at AA range: 21-70 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of hepg2 cells using Antibody diluted at 500. Secondary antibody was diluted at 1:20000
| Cat.No | ADC-13072A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | MYOZ2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol., PBS | Purification Method | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide from Human protein at AA range: 21-70 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NPC6 |
Uniprot Id
Q9NPC6
Target Species
Human
Target Name
MYOZ2
Target Full Name
Myozenin-2
Target Function
Myozenins may serve as intracellular binding proteins involved in linking Z line proteins such as alpha-actinin, gamma-filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis.
Target Involvement
Cardiomyopathy, familial hypertrophic 16 (CMH16)
Target Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line.
Target Protein Families
Myozenin family
Target Tissue Specificity
Expressed specifically in heart and skeletal muscle.
Target Synonyms
C4orf5; Calcineurin binding protein calsarcin 1; Calsarcin 1; Calsarcin-1; Calsarcin1; CMH16; CS 1; CS1; FATZ related protein 2; FATZ-related protein 2; Muscle specific protein; MYOZ 2; MYOZ2; MYOZ2_HUMAN; Myozenin-2; Myozenin2
Target Background
The protein encoded by this gene belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium-dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha-actinin at the z-line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in this gene cause cardiomyopathy familial hypertrophic type 16, a hereditary heart disorder.
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