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The antibody against NAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NAF1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07127A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NAF1 |
| Target Synonyms | NAF1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | K-562, Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 150-400 of human NAF1 (NP_612395.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96HR8 | Immunogen Sequence |
Uniprot Id
Q96HR8
Target Species
Human
Target Name
NAF1
Target Full Name
H/ACA ribonucleoprotein complex non-core subunit NAF1
Target Function
RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
NAF1 family
Target Synonyms
NAF1; H/ACA ribonucleoprotein complex non-core subunit NAF1; hNAF1
Target Background
Enables identical protein binding activity and telomerase RNA binding activity. Involved in regulation of nucleobase-containing compound metabolic process; ribosome biogenesis; and telomerase holoenzyme complex assembly. Located in nucleoplasm. Part of sno(s)RNA-containing ribonucleoprotein complex.
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