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The antibody against NAGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against NAGA was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-00858A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NAGA |
| Target Synonyms | GALB; D22S674; NAGA | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, HL-60, Mouse liver, Mouse lung, Rat testis | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 312-411 of human NAGA (NP_000253.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | IQGRRIHKEKSLIEVYMRPLSNKASALVFFSCRTDMPYRYHSSLGQLNFTGSVIYEAQDVYSGDIISGLRDETNFTVIINPSGVVMWYLYPIKNLEMSQQ | Uniprot ID | P17050 |
Uniprot Id
P17050
Target Species
Human
Target Name
NAGA
Target Full Name
Alpha-N-acetylgalactosaminidase
Target Function
Removes terminal alpha-N-acetylgalactosamine residues from glycolipids and glycopeptides. Required for the breakdown of glycolipids.
Target Involvement
Schindler disease (SCHIND); Kanzaki disease (KANZD)
Target Subcellular Location
Lysosome.
Target Protein Families
Glycosyl hydrolase 27 family
Target Synonyms
NAGA; Alpha-N-acetylgalactosaminidase; EC 3.2.1.49; Alpha-galactosidase B
Target Background
NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).
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