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Rabbit anti-Human NANOS1 Polyclonal Antibody

The antibody against NANOS1 was raised in rabbit using the Synthesized peptide derived from Nanos Homologue 1 (NANOS1) at AA range: 151-200 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-13090A

The antibody against NANOS1 was raised in rabbit using the Synthesized peptide derived from Nanos Homologue 1 (NANOS1) at AA range: 151-200 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-13090A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNANOS1
FormLiquidSpecies ReactivityHuman
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Nanos Homologue 1 (NANOS1) at AA range: 151-200Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8WY41
Background Information
  • Uniprot Id

    Q8WY41

  • Target Species

    Human

  • Target Name

    NANOS1

  • Target Full Name

    Nanos homolog 1

  • Target Function

    May act as a translational repressor which regulates translation of specific mRNAs by forming a complex with PUM2 that associates with the 3'-UTR of mRNA targets. Capable of interfering with the proadhesive and anti-invasive functions of E-cadherin. Up-regulates the production of MMP14 to promote tumor cell invasion.

  • Target Involvement

    Spermatogenic failure 12 (SPGF12)

  • Target Subcellular Location

    Cytoplasm, perinuclear region. Cytoplasm.

  • Target Protein Families

    Nanos family

  • Target Tissue Specificity

    Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermat

  • Target Synonyms

    EC Rep1a; EC_Rep1a; NANO1_HUMAN; NANOS 1; Nanos homolog 1 (Drosophila); Nanos homolog 1; Nanos Homologue 1 (NANOS1); NANOS1; Nos 1; NOS-1; Nos1; OTTHUMP00000046853; Rep 1a; Rep1a

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