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The antibody against NANOS3 was raised in rabbit using the Recombinant Human Nanos homolog 3 protein (21-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against NANOS3 was raised in rabbit using the Recombinant Human Nanos homolog 3 protein (21-192AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human testis tissue using NANOS3 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using NANOS3 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-12582A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NANOS3 |
| Target Synonyms | NANO3_HUMAN antibody; Nanos homolog 3 antibody; NANOS3 antibody; NOS-3 antibody; Nos3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nanos homolog 3 protein (21-192AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P60323 |
Uniprot Id
P60323
Target Species
Human
Target Name
NANOS3
Target Full Name
Nanos homolog 3
Target Function
Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis.
Target Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.
Target Protein Families
Nanos family
Target Tissue Specificity
Ovary, testis and brain (at protein level). In the ovaries, expressed during multiple stages of oogenesis, including primordial, primary, secondary and antral follicles with the highest expression in the oocytes. In the testis, expressed in germ cells, ty
Target Synonyms
NANO3_HUMAN; Nanos homolog 3; NANOS3; NOS-3; Nos3
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