Rabbit anti-Human NBAS Polyclonal Antibody

The antibody against NBAS was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-03900A

Number

Cat.No	ADA-03900A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NBAS
Target Synonyms	NAG; SOPH; ILFS2; NBAS	Form	Liquid
Species Reactivity	Human, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Jurkat, K-562	Application	ELISA, WB, IF/ICC

Cat.No

ADA-03900A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NBAS

Target Synonyms

NAG; SOPH; ILFS2; NBAS

Form

Liquid

Species Reactivity

Human, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Jurkat, K-562

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2).	Target Species	Human
Immunogen Sequence	MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRLLFLRQYIWYS	Uniprot ID	A2RRP1

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human NBAS (NP_056993.2).

Target Species

Human

Immunogen Sequence

MAAPESGPALSPGTAEGEEETILYDLLVNTEWPPETEVQPRGNQKHGASFIITKAIRDRLLFLRQYIWYS

Uniprot ID

A2RRP1

Background Information

Uniprot Id

A2RRP1
Target Species

Human
Target Name

NBAS
Target Full Name

NBAS subunit of NRZ tethering complex
Target Function

Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER.
Target Involvement

Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH); Infantile liver failure syndrome 2 (ILFS2)
Target Subcellular Location

Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Tissue Specificity

Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblas
Target Synonyms

NBAS; NBAS_HUMAN; Neuroblastoma-amplified gene protein; Neuroblastoma-amplified sequence
Target Background

This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly.

Rabbit anti-Human NBAS Polyclonal Antibody

Specifications

Immunogen Information

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