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The antibody against NBAS was raised in rabbit using the Recombinant Human Neuroblastoma-amplified sequence protein (1-70AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against NBAS was raised in rabbit using the Recombinant Human Neuroblastoma-amplified sequence protein (1-70AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human heart tissue using NBAS Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic cancer using NBAS Antibody at dilution of 1:1002
| Cat.No | ADC-16230A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NBAS |
| Target Synonyms | NBAS antibody; NBAS_HUMAN antibody; Neuroblastoma-amplified gene protein antibody; Neuroblastoma-amplified sequence antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Neuroblastoma-amplified sequence protein (1-70AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | A2RRP1 |
Uniprot Id
A2RRP1
Target Species
Human
Target Name
NBAS
Target Full Name
NBAS subunit of NRZ tethering complex
Target Function
Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER.
Target Involvement
Short stature, optic nerve atrophy, and Pelger-Huet anomaly (SOPH); Infantile liver failure syndrome 2 (ILFS2)
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum. Endoplasmic reticulum membrane; Peripheral membrane protein.
Target Tissue Specificity
Broadly expressed, with highest levels in heart and skeletal muscle, and lowest levels in liver, small intestine and thymus. Well expressed in retinal ganglion cells, epidermal skin cells, and leukocytes. Up-regulated together with N-myc in some neuroblas
Target Synonyms
NBAS; NBAS_HUMAN; Neuroblastoma-amplified gene protein; Neuroblastoma-amplified sequence
Target Background
This gene encodes a protein with two leucine zipper domains, a ribosomal protein S14 signature domain and a Sec39 like domain. The protein is thought to be involved in Golgi-to-ER transport. Mutations in this gene are associated with short stature, optic nerve atrophy, and Pelger-Huet anomaly.
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