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Rabbit anti-Human NBEAL2 Polyclonal Antibody

The antibody against NBEAL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1800-2100 of human NBEAL2 (NP_055990.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04829A

The antibody against NBEAL2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1800-2100 of human NBEAL2 (NP_055990.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04829A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNBEAL2
Target SynonymsGPS; BDPLT4; NBEAL2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLaApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 1800-2100 of human NBEAL2 (NP_055990.1).Target SpeciesHuman
Uniprot IDQ6ZNJ1Immunogen Sequence
Background Information
  • Uniprot Id

    Q6ZNJ1

  • Target Species

    Human

  • Target Name

    NBEAL2

  • Target Full Name

    Neurobeachin-like protein 2

  • Target Function

    Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis.

  • Target Involvement

    Gray platelet syndrome (GPS)

  • Target Subcellular Location

    Endoplasmic reticulum.

  • Target Protein Families

    WD repeat neurobeachin family

  • Target Tissue Specificity

    Expressed in megakaryocytes.

  • Target Synonyms

    BDPLT4; GPS; NBEAL2; NBEL2_HUMAN; Neurobeachin-like protein 2; UNQ253/PRO290

  • Target Background

    The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains, and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome.

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