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Rabbit anti-Human NCALD Polyclonal Antibody

The antibody against NCALD was raised in rabbit using the Human NCALD as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47860A

The antibody against NCALD was raised in rabbit using the Human NCALD as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47860A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCALD
Target SynonymsNCALD antibody; Neurocalcin-delta antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NCALDTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP61601
Background Information
  • Uniprot Id

    P61601

  • Target Species

    Human

  • Target Name

    NCALD

  • Target Full Name

    Neurocalcin-delta

  • Target Function

    May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.

  • Target Protein Families

    Recoverin family

  • Target Tissue Specificity

    Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    NCALD; Neurocalcin-delta

  • Target Background

    This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.

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