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Rabbit anti-Human NCAPD3 Polyclonal Antibody

The antibody against NCAPD3 was raised in rabbit using the Human NCAPD3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47858A

The antibody against NCAPD3 was raised in rabbit using the Human NCAPD3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47858A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCAPD3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NCAPD3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP42695
Background Information
  • Uniprot Id

    P42695

  • Target Species

    Human

  • Target Name

    NCAPD3

  • Target Full Name

    Condensin-2 complex subunit D3

  • Target Function

    Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Specifically required for decatenation of centromeric ultrafine DNA bridges during anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size.

  • Target Subcellular Location

    Nucleus.

  • Target Synonyms

    CAP D3; CAPD 3; CAPD3; CNDD3_HUMAN; Condensin II complex subunit D3; Condensin-2 complex subunit D3; FLJ42888; hCAP-D3; Hcp 6; Hcp6; hHCP 6; hHCP6; KIAA0056; MGC104671; NCAPD 3; Ncapd3; Non SMC condensin II complex subunit D3; Non-SMC condensin II complex subunit D3; OTTHUMP00000235403; OTTHUMP00000235404

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