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Rabbit anti-Human NCDN Polyclonal Antibody

The antibody against NCDN was raised in rabbit using the Recombinant Human Neurochondrin protein (403-516AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-05957A

The antibody against NCDN was raised in rabbit using the Recombinant Human Neurochondrin protein (403-516AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-05957A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCDN
Target SynonymsNCDN antibody; KIAA0607 antibody; Neurochondrin antibodyFormLiquid
Species ReactivityHuman, RatIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Neurochondrin protein (403-516AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBB6
Background Information
  • Uniprot Id

    Q9UBB6

  • Target Species

    Human

  • Target Name

    NCDN

  • Target Full Name

    Neurochondrin

  • Target Function

    Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling. Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin-concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.

  • Target Subcellular Location

    Cytoplasm, cytosol. Endosome membrane; Lipid-anchor. Cell projection, dendrite. Cell junction, synapse, postsynapse.

  • Target Protein Families

    Neurochondrin family

  • Target Tissue Specificity

    Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord. Weakly expressed in ovary, testis, fetal brain and small intestine.

  • Target Synonyms

    NCDN; KIAA0607; Neurochondrin

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