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Rabbit anti-Human NCEH1 Polyclonal Antibody

The antibody against NCEH1 was raised in rabbit using the Fusion protein of Human NCEH1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-31160A

The antibody against NCEH1 was raised in rabbit using the Fusion protein of Human NCEH1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-31160A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCEH1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human NCEH1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6PIU2
Background Information
  • Uniprot Id

    Q6PIU2

  • Target Species

    Human

  • Target Name

    NCEH1

  • Target Full Name

    Neutral cholesterol ester hydrolase 1

  • Target Function

    Hydrolyzes 2-acetyl monoalkylglycerol ether, the penultimate precursor of the pathway for de novo synthesis of platelet-activating factor. May be responsible for cholesterol ester hydrolysis in macrophages. Also involved in organ detoxification by hydrolyzing exogenous organophosphorus compounds. May contribute to cancer pathogenesis by promoting tumor cell migration.

  • Target Subcellular Location

    Cell membrane; Single-pass type II membrane protein. Microsome.

  • Target Protein Families

    'GDXG' lipolytic enzyme family

  • Target Tissue Specificity

    Expressed in monocyte-derived macrophages. Up-regulated in invasive melanoma and breast carcinoma cell lines.

  • Target Synonyms

    Arylacetamide deacetylase like 1; Arylacetamide deacetylase-like 1; NCEH; Nceh1; NCEH1_HUMAN; Neutral cholesterol ester hydrolase 1; Neutral cholesterol ester hydrolase

  • Target Background

    Predicted to enable hydrolase activity. Predicted to be involved in ether lipid metabolic process. Predicted to act upstream of or within SMAD protein signal transduction; protein dephosphorylation; and xenobiotic metabolic process. Located in membrane.

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