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The antibody against NCOA4 was raised in rabbit using the Recombinant Human Nuclear receptor coactivator 4 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against NCOA4 was raised in rabbit using the Recombinant Human Nuclear receptor coactivator 4 protein (1-280AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human kidney tissue using NCOA4 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using NCOA4 Antibody at dilution of 1:1002
Immunofluorescent analysis of MCF-7 cells using NCOA4 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-44557A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NCOA4 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nuclear receptor coactivator 4 protein (1-280AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q13772 |
Uniprot Id
Q13772
Target Species
Human
Target Name
NCOA4
Target Full Name
Nuclear receptor coactivator 4
Target Function
Enhances the androgen receptor transcriptional activity in prostate cancer cells. Ligand-independent coactivator of the peroxisome proliferator-activated receptor (PPAR) gamma.
Target Involvement
A chromosomal aberration involving NCOA4 is found in papillary thyroid carcinomas (PTCs). Inversion inv(10)(q11.2;q11.2) generates the RET/NCOA4 (PTC3) oncogene.
Target Tissue Specificity
Widely expressed. Also detected in adipose tissues and in different cell lines. Isoform Beta is only expressed in testis.
Target Synonyms
70 kDa androgen receptor activator; 70 kDa androgen receptor coactivator; 70 kDa AR activator; 70 kDa AR-activator; Androgen receptor coactivator 70 kD; Androgen receptor coactivator 70 kDa protein; Androgen receptor-associated protein of 70 kDa; ARA 70; ARA70; DKFZp762E1112; ELE 1; ELE1; ELE1/ret TK; NCOA 4; NCoA-4; NCOA4; NCOA4_HUMAN; Nuclear receptor coactivator 4; Papillary thyroid carcinoma 3; PTC 3; PTC3; RET activating gene ELE1; Ret activating protein ELE1; Ret-activating protein ELE1; RFG
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