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Rabbit anti-Human NCR1 Polyclonal Antibody

The antibody against NCR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 151-303 of human NCR1 (NP_001138929.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11424A

The antibody against NCR1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 151-303 of human NCR1 (NP_001138929.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11424A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCR1
Target SynonymsLY94; CD335; NKP46; NK-p46; NCR1FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesRat spleenApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 151-303 of human NCR1 (NP_001138929.2).Target SpeciesHuman
Immunogen SequenceSMFLLLKEGRSSHVQRGYGKVQAEFPLGPVTTAHRGTYRCFGSYNNHAWSFPSEPVKLLVTGDIENTSLAPEDPTFPDTWGTYLLTTETGLQKDHALWDHTAQNLLRMGLAFLVLVALVWFLVEDWLSRKRTRERASRASTWEGRRRLNTQTLUniprot IDO76036
Background Information
  • Uniprot Id

    O76036

  • Target Species

    Human

  • Target Name

    NCR1

  • Target Full Name

    Natural cytotoxicity triggering receptor 1

  • Target Function

    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Natural cytotoxicity receptor (NCR) family

  • Target Tissue Specificity

    Selectively expressed by both resting and activated NK cells.

  • Target Synonyms

    NCR1; LY94; Natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein; NK-p46; NKp46; hNKp46; CD antigen CD335

  • Target Background

    Predicted to be involved in cellular defense response; regulation of natural killer cell mediated cytotoxicity; and signal transduction. Predicted to act upstream of or within defense response to virus and detection of virus. Predicted to be located in cell surface. Predicted to be part of SWI/SNF complex. Predicted to be active in plasma membrane. Biomarker of acquired immunodeficiency syndrome; anogenital venereal wart; hepatitis C; and lymphoproliferative syndrome.

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