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Rabbit anti-Human NCR2 Polyclonal Antibody

The antibody against NCR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04085A

The antibody against NCR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04085A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNCR2
Target SynonymsLY95; CD336; NKP44; NK-p44; dJ149M18.1; NCR2FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesRajiApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 22-192 of human NCR2 (NP_004819.2).Target SpeciesHuman
Immunogen SequenceQSKAQVLQSVAGQTLTVRCQYPPTGSLYEKKGWCKEASALVCIRLVTSSKPRTMAWTSRFTIWDDPDAGFFTVTMTDLREEDSGHYWCRIYRPSDNSVSKSVRFYLVVSPASASTQTSWTPRDLVSSQTQTQSCVPPTAGARQAPESPSTIPVPSQPQNSTLRPGPAAPIAUniprot IDO95944
Background Information
  • Uniprot Id

    O95944

  • Target Species

    Human

  • Target Name

    NCR2

  • Target Full Name

    Natural cytotoxicity triggering receptor 2

  • Target Function

    Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

  • Target Subcellular Location

    Cell membrane; Single-pass type I membrane protein.

  • Target Protein Families

    Natural cytotoxicity receptor (NCR) family

  • Target Tissue Specificity

    Selectively expressed by activated NK cells and by in vitro cultured (i.e. activated) TCRg/d lymphoid cells.

  • Target Synonyms

    NCR2; LY95; Natural cytotoxicity triggering receptor 2; Lymphocyte antigen 95 homolog; NK cell-activating receptor; Natural killer cell p44-related protein; NK-p44; NKp44; CD antigen CD336

  • Target Background

    Predicted to enable signaling receptor activity. Predicted to be involved in cellular defense response and signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Predicted to be active in cell surface.

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