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Rabbit anti-Human NEMF Polyclonal Antibody

The antibody against NEMF was raised in rabbit using the Synthesized peptide derived from internal of Human SDCG1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-42216A

The antibody against NEMF was raised in rabbit using the Synthesized peptide derived from internal of Human SDCG1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-42216A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNEMF
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from internal of Human SDCG1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO60524
Background Information
  • Uniprot Id

    O60524

  • Target Species

    Human

  • Target Name

    NEMF

  • Target Full Name

    Ribosome quality control complex subunit NEMF

  • Target Function

    Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex. May indirectly play a role in nuclear export.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    NEMF family

  • Target Tissue Specificity

    Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.

  • Target Synonyms

    1500011I12Rik; 4933405E14Rik; Antigen NY-CO-1; FLJ10051 ; Nemf; NEMF_HUMAN; Nuclear export mediator factor Nemf; NY CO 1; SDCCAG1; SDCG1; Serologically defined colon cancer antigen 1

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