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Rabbit anti-Human NF1 Polyclonal Antibody

The antibody against NF1 was raised in rabbit using the Recombinant Human Neurofibromin protein (655-892AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

ADC-09148A

The antibody against NF1 was raised in rabbit using the Recombinant Human Neurofibromin protein (655-892AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-09148A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNF1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Neurofibromin protein (655-892AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP21359
Background Information
  • Uniprot Id

    P21359

  • Target Species

    Human

  • Target Name

    NF1

  • Target Full Name

    Neurofibromin

  • Target Function

    Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity.

  • Target Involvement

    Neurofibromatosis 1 (NF1); Leukemia, juvenile myelomonocytic (JMML); Watson syndrome (WTSN); Familial spinal neurofibromatosis (FSNF); Neurofibromatosis-Noonan syndrome (NFNS); Colorectal cancer (CRC)

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Tissue Specificity

    Detected in brain, peripheral nerve, lung, colon and muscle.

  • Target Research Area

    Cancer

  • Target Synonyms

    DKFZp686J1293; FLJ21220; Neurofibromatosis Noonan syndrome; Neurofibromatosis related protein NF 1; Neurofibromatosis related protein NF1; neurofibromatosis type I; Neurofibromatosis-related protein NF-1; Neurofibromin 1; Neurofibromin truncated; Neurofibromin1; NF 1; NF; NF1; NF1_HUMAN; NFNS; Type 1 Neurofibromatosis; von Recklinghausen disease neurofibromin; von Recklinghausen disease related protein VRNF; VRNF; WATS; Watson disease related protein WSS; Watson syndrome; WSS

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