Rabbit anti-Human NFATC2IP Polyclonal Antibody

The antibody against NFATC2IP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 290-360 of human NFATC2IP (NP_116204.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09997A

Number

Cat.No	ADA-09997A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NFATC2IP
Target Synonyms	ESC2; NIP45; RAD60; NFATC2IP	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	LO2, U-87MG	Application	ELISA, WB

Cat.No

ADA-09997A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NFATC2IP

Target Synonyms

ESC2; NIP45; RAD60; NFATC2IP

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

LO2, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 290-360 of human NFATC2IP (NP_116204.3).	Target Species	Human
Immunogen Sequence	VDHMATHLGVSPSRILLLFGETELSPTATPRTLKLGVADIIDCVVLTSSPEATETSQQLQLRVQGKEKHQT	Uniprot ID	Q8NCF5

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 290-360 of human NFATC2IP (NP_116204.3).

Target Species

Human

Immunogen Sequence

VDHMATHLGVSPSRILLLFGETELSPTATPRTLKLGVADIIDCVVLTSSPEATETSQQLQLRVQGKEKHQT

Uniprot ID

Q8NCF5

Background Information

Uniprot Id

Q8NCF5
Target Species

Human
Target Name

NFATC2IP
Target Full Name

NFATC2-interacting protein
Target Function

In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Synonyms

45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; cytoplasmic 2-interacting protein; ESC2; NF2IP_HUMAN; NFAT-interacting protein, 45-KD; NFATC2-interacting protein; Nfatc2ip; NIP45; Nuclear factor of activated T-cells; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60
Target Background

Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus.

Rabbit anti-Human NFATC2IP Polyclonal Antibody

Specifications

Immunogen Information

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