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The antibody against NFATC2IP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NFATc2IP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NFATC2IP was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NFATc2IP. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
| Cat.No | ADC-33539A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFATC2IP |
| Target Synonyms | 45 kDa NF-AT-interacting protein antibody; 45 kDa NFAT-interacting protein antibody; cytoplasmic 2-interacting protein antibody; ESC2 antibody; NF2IP_HUMAN antibody; NFAT-interacting protein, 45-KD antibody; NFATC2-interacting protein antibody; Nfatc2ip antibody; NIP45 antibody; Nuclear factor of activated T-cells antibody; Nuclear factor of activated T-cells, calcineurin-dependent 2 interacting protein antibody; RAD60 antibody, cytoplasmic, cytoplasmic 2-interacting protein antibody; nuclear factor of activated T-cells | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human NFATc2IP. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8NCF5 |
Uniprot Id
Q8NCF5
Target Species
Human
Target Name
NFATC2IP
Target Full Name
NFATC2-interacting protein
Target Function
In T-helper 2 (Th2) cells, regulates the magnitude of NFAT-driven transcription of a specific subset of cytokine genes, including IL3, IL4, IL5 and IL13, but not IL2. Recruits PRMT1 to the IL4 promoter; this leads to enhancement of histone H4 'Arg-3'-methylation and facilitates subsequent histone acetylation at the IL4 locus, thus promotes robust cytokine expression. Down-regulates formation of poly-SUMO chains by UBE2I/UBC9.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
45 kDa NF-AT-interacting protein; 45 kDa NFAT-interacting protein; cytoplasmic 2-interacting protein; ESC2; NF2IP_HUMAN; NFAT-interacting protein, 45-KD; NFATC2-interacting protein; Nfatc2ip; NIP45; Nuclear factor of activated T-cells; Nuclear factor of activated T-cells, cytoplasmic 2-interacting protein; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein; RAD60
Target Background
Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus.
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