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Rabbit anti-Human NFIB / NF1B2 Monoclonal Antibody

The antibody against NFIB / NF1B2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 321-420 of human NFIB / NF1B2 (NP_005587.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13248A

The antibody against NFIB / NF1B2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 321-420 of human NFIB / NF1B2 (NP_005587.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13248A ClonalityMonoclonal
Host SpeciesRabbitTarget NameNFIB / NF1B2
Target SynonymsCTF; MACID; NF1-B; NFI-B; NFIB2; NFIB3; NF-I/B; NFI-RED; HMGIC/NFIB; NFIB / NF1B2FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse lung, SH-SY5YApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 321-420 of human NFIB / NF1B2 (NP_005587.2).Target SpeciesHuman
Immunogen SequenceKPLFSSASPQDSSPRLSTFPQHHHPGIPGVAHSVISTRTPPPPSPLPFPTQAILPPAPSSYFSHPTIRYPPHLNPQDTLKNYVPSYDPSSPQTSQSWYLGUniprot IDO00712
Background Information
  • Uniprot Id

    O00712

  • Target Species

    Human

  • Target Name

    NFIB

  • Target Full Name

    Nuclear factor 1 B-type

  • Target Function

    Transcriptional activator of GFAP, essential for proper brain development. Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    CTF/NF-I family

  • Target Synonyms

    CCAAT Box Binding Transcription Factor; CCAAT-box-binding transcription factor; CTF; HMGIC/NFIB; NF-I/B; NF1-B; NF1B; NF1B2; NFI-B; NFI-RED; Nfib; NFIB_HUMAN; NFIB2; NFIB3; Nuclear factor 1 B-type; Nuclear factor 1/B; Nuclear Factor 1B; Nuclear Factor I B; Nuclear factor I/B; TGGCA Binding Protein; TGGCA-binding protein; TRANSCRIPTION FACTOR NFIB

  • Target Background

    Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription regulator inhibitor activity. Involved in brain development; negative regulation of DNA binding activity; and regulation of transcription by RNA polymerase II. Located in fibrillar center and nucleoplasm.

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