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The antibody against NFIC was raised in rabbit using the Recombinant Human Nuclear factor 1 C-type protein (201-428AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against NFIC was raised in rabbit using the Recombinant Human Nuclear factor 1 C-type protein (201-428AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human lung tissue using NFIC Antibody at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using NFIC Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-21795A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFIC |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nuclear factor 1 C-type protein (201-428AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P08651 |
Uniprot Id
P08651
Target Species
Human
Target Name
NFIC
Target Full Name
Nuclear factor 1 C-type
Target Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Target Subcellular Location
Nucleus.
Target Protein Families
CTF/NF-I family
Target Synonyms
1110019L22Rik; 1500041O16Rik; AA589446; AI746521; CAAT box transcription factor; CCAAT binding transcription factor ; CCAAT box binding transcription factor ; CCAAT-box-binding transcription factor; CNFI C; CTF; CTF5; MGC137374; MGC20153; NF I; NF I/C; NF-I/C; NF1 C; NF1-C; NF1C; NFI; NFI-C; NFI/C; NFIC; NFIC_HUMAN; Nuclear factor 1; Nuclear factor 1 C type; Nuclear factor 1 C-type; Nuclear factor 1/C; Nuclear factor I/C (CCAAT binding transcription factor); Nuclear factor I/C; TGGCA binding protein; TGGCA-binding protein; Transcription factor NFIC
Target Background
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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