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The antibody against NFIX was raised in rabbit using the Recombinant Human Nuclear factor 1 X-type protein (201-440AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against NFIX was raised in rabbit using the Recombinant Human Nuclear factor 1 X-type protein (201-440AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human tonsil tissue using NFIX Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human kidney tissue using NFIX Antibody at dilution of 1:1002
| Cat.No | ADC-20308A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NFIX |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nuclear factor 1 X-type protein (201-440AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14938 |
Uniprot Id
Q14938
Target Species
Human
Target Name
NFIX
Target Full Name
Nuclear factor 1 X-type
Target Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Target Involvement
Sotos syndrome 2 (SOTOS2); Marshall-Smith syndrome (MRSHSS)
Target Subcellular Location
Nucleus.
Target Protein Families
CTF/NF-I family
Target Tissue Specificity
Widely expressed.
Target Synonyms
CCAAT box binding transcription factor; CCAAT-box-binding transcription factor; CTF; NF-I/X; NF1-X; NF1A; NF1X; NFI X; NFI-X; NFI/X; NFIX; NFIX_HUMAN; Nuclear factor 1 X type; Nuclear factor 1 X-type; Nuclear factor 1/X; Nuclear factor I/X; TGGCA binding protein; TGGCA-binding protein
Target Background
The protein encoded by this gene is a transcription factor that binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3 in viral and cellular promoters. The encoded protein can also stimulate adenovirus replication in vitro. Three transcript variants encoding different isoforms have been found for this gene.
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