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Rabbit anti-Human NFX1 Polyclonal Antibody

The antibody against NFX1 was raised in rabbit using the Human NFX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47817A

The antibody against NFX1 was raised in rabbit using the Human NFX1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-47817A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNFX1
Target SynonymsNFX1 antibody; NFX2 antibody; Transcriptional repressor NF-X1 antibody; EC 2.3.2.- antibody; Nuclear transcription factor antibody; X box-binding protein 1 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium AzidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NFX1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ12986
Background Information
  • Uniprot Id

    Q12986

  • Target Species

    Human

  • Target Name

    NFX1

  • Target Full Name

    Transcriptional repressor NF-X1

  • Target Function

    Binds to the X-box motif of MHC class II genes and represses their expression. May play an important role in regulating the duration of an inflammatory response by limiting the period in which MHC class II molecules are induced by interferon-gamma. Isoform 3 binds to the X-box motif of TERT promoter and represses its expression. Together with PABPC1 or PABPC4, isoform 1 acts as a coactivator for TERT expression. Mediates E2-dependent ubiquitination.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    NFX1 family

  • Target Synonyms

    NFX1; NFX2; Transcriptional repressor NF-X1; EC 2.3.2.-; Nuclear transcription factor; X box-binding protein 1

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