Rabbit anti-Human NGRN Polyclonal Antibody

The antibody against NGRN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human NGRN (NP_001028260.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-02188A

Number

Cat.No	ADA-02188A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NGRN
Target Synonyms	DSC92; NGRN	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.01% thimerosal, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, 293T, A-549, U-87MG	Application	ELISA, WB

Cat.No

ADA-02188A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NGRN

Target Synonyms

DSC92; NGRN

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.01% thimerosal, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, 293T, A-549, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human NGRN (NP_001028260.2).	Target Species	Human
Uniprot ID	Q9NPE2	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 62-291 of human NGRN (NP_001028260.2).

Target Species

Human

Uniprot ID

Q9NPE2

Immunogen Sequence

Background Information

Uniprot Id

Q9NPE2
Target Species

Human
Target Name

NGRN
Target Full Name

Neugrin
Target Function

Plays an essential role in mitochondrial ribosome biogenesis. As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mitochondrial ribosomal RNA (16S mt-rRNA), controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation of core subunits of the oxidative phosphorylation system.
Target Subcellular Location

Nucleus. Secreted. Mitochondrion membrane.
Target Protein Families

Neugrin family
Target Tissue Specificity

Expressed at high levels in heart, brain and skeletal muscle. In brain, mainly expressed in neurons rather than glial cells.
Target Synonyms

DSC92; FI58Gm; Mesenchymal stem cell protein DSC92; Neugrin; Neugrin neurite outgrowth associated ; Neurite outgrowth associated protein ; Neurite outgrowth-associated protein; Ngrn; NGRN_HUMAN; Spinal cord-derived protein FI58G
Target Background

Enables rRNA binding activity. Involved in positive regulation of mitochondrial translation. Located in several cellular components, including intercellular bridge; mitotic spindle; and nuclear body.

Rabbit anti-Human NGRN Polyclonal Antibody

Specifications

Immunogen Information

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