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Rabbit anti-Human NHP2L1 Polyclonal Antibody

The antibody against SNU13 was raised in rabbit using the Human NHP2L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-47812A

The antibody against SNU13 was raised in rabbit using the Human NHP2L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-47812A ClonalityPolyclonal
Host SpeciesRabbitTarget NameSNU13
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NHP2L1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP55769
Background Information
  • Uniprot Id

    P55769

  • Target Species

    Human

  • Target Name

    SNU13

  • Target Full Name

    NHP2-like protein 1

  • Target Function

    Involved in pre-mRNA splicing as component of the spliceosome. Binds to the 5'-stem-loop of U4 snRNA and thereby contributes to spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.

  • Target Subcellular Location

    Nucleus. Nucleus, nucleolus.

  • Target Protein Families

    Eukaryotic ribosomal protein eL8 family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Research Area

    Transcription

  • Target Synonyms

    SNU13; NHP2L1; NHP2-like protein 1; High mobility group-like nuclear protein 2 homolog 1; OTK27; SNU13 homolog; hSNU13; U4/U6.U5 small nuclear ribonucleoprotein SNU13; U4/U6.U5 tri-snRNP 15.5 kDa protein) [Cleaved into: NHP2-like protein 1; N-terminally processed]

  • Target Background

    Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene.

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