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The antibody against NKIRAS2 was raised in rabbit using the Human NKIRAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
The antibody against NKIRAS2 was raised in rabbit using the Human NKIRAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA.
$600.00
| Cat.No | ADC-52561A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NKIRAS2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Human NKIRAS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NYR9 |
Uniprot Id
Q9NYR9
Target Species
Human
Target Name
NKIRAS2
Target Full Name
NF-kappa-B inhibitor-interacting Ras-like protein 2
Target Function
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Small GTPase superfamily, Ras family, KappaB-Ras subfamily
Target Tissue Specificity
Widely expressed.
Target Synonyms
DKFZP434N1526; I kappa B interacting Ras like protein 2; I-kappa-B-interacting Ras-like protein 2; Kappa B Ras protein 2; Kappa B-Ras protein 2; KappaB Ras2; KappaB-Ras2; KBRAS 2; KBRAS2; KBRS2_HUMAN; MGC74742; NF kappa B inhibitor interacting Ras like protein 2; NF-kappa-B inhibitor-interacting Ras-like protein 2; NFKB inhibitor interacting Ras like 2; NFKB inhibitor interacting Ras like protein 2; NKIRAS 2; NKIRAS2
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