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The antibody against NLRC5 was raised in Rabbit using the recombinant protein of human NLRC5 as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NLRC5 was raised in Rabbit using the recombinant protein of human NLRC5 as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-06502A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NLRC5 |
| Target Synonyms | NOD4; NOD27; CLR16.1; NLRC5 | Form | Liquid |
| Species Reactivity | Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse lung | Application | ELISA, WB |
| Immunogen Description | Recombinant protein of human NLRC5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86WI3 |
Uniprot Id
Q86WI3
Target Species
Human
Target Name
NLRC5
Target Full Name
Protein NLRC5
Target Function
Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms.
Target Subcellular Location
Cytoplasm.
Target Protein Families
NLRP family
Target Tissue Specificity
Expressed in spleen, thymus, lung, brain, tonsil, heart and prostate.
Target Synonyms
Caterpiller protein 16.1; CLR16.1; FLJ21709; FLJ39711; NLR family, CARD domain containing 5; NLR family, CARD-containing 5; NLR family, caspase recruitment domain-containing 5; NLRC5; NLRC5_HUMAN; NOD-like receptor C5; NOD27; NOD4; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4; nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 5 ; nucleotide-binding oligomerization domains 27; OTTHUMP00000164675; Protein Caterpiller 16.1; Protein NLRC5
Target Background
This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways.
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