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The antibody against NLRP4 was raised in rabbit using the Synthetic peptide of Human NLRP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against NLRP4 was raised in rabbit using the Synthetic peptide of Human NLRP4 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26319A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NLRP4 |
| Target Synonyms | Cancer/testis antigen 58 antibody; CLR19.5 antibody; CT58 antibody; FLJ32126 antibody; NACHT, leucine rich repeat and PYD containing 4 antibody; NACHT, LRR and PYD containing protein 4 antibody; NACHT, LRR and PYD domains-containing protein 4 antibody; NALP4_HUMAN antibody; NLR family, pyrin domain containing 4 antibody; NLRP4 antibody; Nucleotide binding oligomerization domain | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human NLRP4 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96MN2 |
Uniprot Id
Q96MN2
Target Species
Human
Target Name
NLRP4
Target Full Name
NACHT, LRR and PYD domains-containing protein 4
Target Function
May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors. Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, and its subsequent degradation. Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, suggesting that it operates at a point of convergence in these two cytokine signaling pathways.
Target Protein Families
NLRP family
Target Synonyms
Cancer/testis antigen 58; CLR19.5; CT58; FLJ32126; NACHT, leucine rich repeat and PYD containing 4; NACHT, LRR and PYD containing protein 4; NACHT, LRR and PYD domains-containing protein 4; NALP4_HUMAN; NLR family, pyrin domain containing 4; NLRP4; Nucleotide binding oligomerization domain, leucine rich repeat and pyrin domain containing 4; PAAD and NACHT containing protein 2; PAAD and NACHT-containing protein 2; PAN2; PYPAF4; PYRIN and NACHT-containing protein 2; PYRIN containing APAF1 like protein 4; PYRIN-containing APAF1-like protein 4; Ribonuclease inhibitor 2; RNH2
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