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The antibody against NMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human NMB (NP_066563.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NMB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human NMB (NP_066563.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-02209A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NMB |
| Target Synonyms | NMB | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, Mouse brain, PC-12, SKOV3 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-121 of human NMB (NP_066563.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MARRAGGARMFGSLLLFALLAAGVAPLSWDLPEPRSRASKIRVHSRGNLWATGHFMGKKSLEPSSPSPLGTAPHTSLRDQRLQLSHDLLGILLLKKALGVSLSRPAPQIQYRRLLVQILQK | Uniprot ID | P08949 |
Uniprot Id
P08949
Target Species
Human
Target Name
NMB
Target Full Name
Neuromedin-B
Target Function
Stimulates smooth muscle contraction in a manner similar to that of bombesin.
Target Subcellular Location
Secreted.
Target Protein Families
Bombesin/neuromedin-B/ranatensin family
Target Synonyms
NMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]
Target Background
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.
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