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The antibody against NMU was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Neuromedin-U. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against NMU was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Neuromedin-U. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of HepG2 cells using Neuromedin-U Polyclonal Antibody
| Cat.No | ADC-38104A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NMU |
| Target Synonyms | Neuromedin U 25 antibody; Neuromedin U antibody; Neuromedin-U-25 antibody; NmU 25 antibody; NMU antibody; NmU-25 antibody; NMU_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human Neuromedin-U. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P48645 |
Uniprot Id
P48645
Target Species
Human
Target Name
NMU
Target Full Name
Neuromedin-U
Target Function
Ligand for receptors NMUR1 and NMUR2. Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder.; Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release although its potency is much lower than that of neuromedin precursor-related peptide 36.; Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system.
Target Subcellular Location
Secreted.
Target Protein Families
NmU family
Target Tissue Specificity
Expressed throughout the enteric nervous system with highest levels being found in the jejunum.
Target Synonyms
Neuromedin U 25; Neuromedin U; Neuromedin-U-25; NmU 25; NMU; NmU-25; NMU_HUMAN
Target Background
This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.
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