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The antibody against NODAL was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Nodal. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against NODAL was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Nodal. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western blot analysis of Hela lysis using NODAL antibody.. Secondary antibody was diluted at 1:20000
Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:1002
| Cat.No | ADC-13132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NODAL |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human Nodal. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96S42 |
Uniprot Id
Q96S42
Target Species
Human
Target Name
NODAL
Target Full Name
Nodal homolog
Target Function
Essential for mesoderm formation and axial patterning during embryonic development.
Target Involvement
Heterotaxy, visceral, 5, autosomal (HTX5)
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family
Target Synonyms
HTX5; MGC138230; Nodal; Nodal Growth Differentiation Factor; nodal homolog (mouse); Nodal homolog; Nodal; Mouse; Homolog; NODAL_HUMAN
Target Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis.
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