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Rabbit anti-Human NOLC1 Polyclonal Antibody

The antibody against NOLC1 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human NOLC1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

ADC-41063A

The antibody against NOLC1 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human NOLC1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.

$297.00

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Specifications


Cat.No ADC-41063A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNOLC1
FormLiquidSpecies ReactivityHuman, Mouse, Rat
Storage BufferPH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+)Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from C-terminal of Human NOLC1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ14978
Background Information
  • Uniprot Id

    Q14978

  • Target Species

    Human

  • Target Name

    NOLC1

  • Target Full Name

    Nucleolar and coiled-body phosphoprotein 1

  • Target Function

    Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification. Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification. Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities.

  • Target Subcellular Location

    Nucleus, nucleolus. Cytoplasm.

  • Target Synonyms

    140 kDa nucleolar phosphoprotein; HCV NS5A trans regulated protein 13; HCV NS5A transactivated protein 13; HCV NS5A-transactivated protein 13; Hepatitis C virus NS5A transactivated protein 13; Hepatitis C virus NS5A-transactivated protein 13; KIAA0035; NOLC 1; NOLC1; NOLC1_HUMAN; NOPP 130; NOPP 140; NOPP130; Nopp140; NS5ATP13; Nucleolar 130 kDa protein; Nucleolar and coiled body phosphoprotein 1; Nucleolar and coiled body phosphprotein 1; Nucleolar and coiled-body phosphoprotein 1; Nucleolar phosphoprotein p130; Nucleolar protein p130; P130

  • Target Background

    Enables protein heterodimerization activity and protein-macromolecule adaptor activity. Involved in neural crest cell development; neural crest formation; and regulation of translation. Located in fibrillar center.

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