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The antibody against NOMO1 was raised in rabbit using the Recombinant Human Nodal modulator 1 protein (918-1044AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against NOMO1 was raised in rabbit using the Recombinant Human Nodal modulator 1 protein (918-1044AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-05939A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NOMO1 |
| Target Synonyms | Nodal modulator 1 antibody; NOMO 1 antibody; Nomo antibody; NOMO1 antibody; NOMO1_HUMAN antibody; PM5 antibody; pM5 protein antibody; pM5 protein telomeric copy antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Biotin conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Nodal modulator 1 protein (918-1044AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15155 |
Uniprot Id
Q15155
Target Species
Human
Target Name
NOMO1
Target Full Name
BOS complex subunit NOMO1
Target Function
Component of a ribosome-associated endoplasmic reticulum (ER) translocon complex involved in multi-pass membrane protein transport into the ER membrane and biogenesis. May antagonize Nodal signaling and subsequent organization of axial structures during mesodermal patterning, via its interaction with NCLN/Nicalin.
Target Subcellular Location
Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Tissue Specificity
Expressed in colon tumor tissue and in adjacent normal colonic mucosa.
Target Synonyms
Nodal modulator 1; NOMO 1 ; Nomo; NOMO1; NOMO1_HUMAN; PM5; pM5 protein; pM5 protein telomeric copy
Target Background
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE).
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