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The antibody against NOX3 was raised in rabbit using the Recombinant Human NADPH oxidase 3 protein (223-395AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against NOX3 was raised in rabbit using the Recombinant Human NADPH oxidase 3 protein (223-395AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using NOX3 Antibody at dilution of 1:100
| Cat.No | ADC-16337A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NOX3 |
| Target Synonyms | NOX3; MOX2; NADPH oxidase 3; Mitogenic oxidase 2; MOX-2; gp91phox homolog 3; GP91-3 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human NADPH oxidase 3 protein (223-395AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9HBY0 |
Uniprot Id
Q9HBY0
Target Species
Human
Target Name
NOX3
Target Full Name
NADPH oxidase 3
Target Function
NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
Target Subcellular Location
Membrane; Multi-pass membrane protein.
Target Synonyms
NOX3; MOX2; NADPH oxidase 3; Mitogenic oxidase 2; MOX-2; gp91phox homolog 3; GP91-3
Target Background
This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
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