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The antibody against NPHS2 was raised in rabbit using the Human NPHS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against NPHS2 was raised in rabbit using the Human NPHS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-47785A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NPHS2 |
| Target Synonyms | idiopathic, nephrosis 2 antibody; Nephrosis 2, steroid resistant (podocin) antibody; nephrosis 2, steroid resistant antibody; NPHS2 antibody; NPHS2 gene antibody; PDCN antibody; PODO_HUMAN antibody; Podocin antibody; SRN1 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, WB |
| Storage | Upon receipt |
| Immunogen Description | Human NPHS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NP85 |
Uniprot Id
Q9NP85
Target Species
Human
Target Name
NPHS2
Target Full Name
Podocin
Target Function
Plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.
Target Involvement
Nephrotic syndrome 2 (NPHS2)
Target Subcellular Location
[Isoform 1]: Cell membrane; Peripheral membrane protein.; [Isoform 2]: Endoplasmic reticulum.
Target Protein Families
Band 7/mec-2 family
Target Tissue Specificity
Almost exclusively expressed in the podocytes of fetal and mature kidney glomeruli.
Target Research Area
Cell Biology
Target Synonyms
nephrosis 2; Nephrosis 2, idiopathic, steroid resistant (podocin); nephrosis 2, idiopathic, steroid resistant; NPHS2; NPHS2 gene; PDCN; PODO_HUMAN; Podocin; SRN1
Target Background
This gene encodes a protein that plays a role in the regulation of glomerular permeability. Mutations in this gene cause steroid-resistant nephrotic syndrome. Alternative splicing results in multiple transcript variants.
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