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The antibody against NQO2 was raised in rabbit using the Human NQO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against NQO2 was raised in rabbit using the Human NQO2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-47780A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NQO2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human NQO2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P16083 |
Uniprot Id
P16083
Target Species
Human
Target Name
NQO2
Target Full Name
Ribosyldihydronicotinamide dehydrogenase [quinone]
Target Function
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Target Subcellular Location
Cytoplasm.
Target Protein Families
NAD(P)H dehydrogenase (quinone) family
Target Synonyms
DHQV; DIA6; EC 1.10.99.2; MGC94180; NAD(P)H dehydrogenase quinone 2; NAD(P)H menadione oxidoreductase 1 dioxin inducible 2; NAD(P)H menadione oxidoreductase 2 dioxin inducible ; NMOR2; NQO 2; NQO2; NQO2_HUMAN; NRH dehydrogenase [quinone] 2; NRH dehydrogenase; NRH:quinone oxidoreductase 2; OTTHUMP00000015948; OTTHUMP00000015949; OTTHUMP00000015953; Ox 2; Ox2; QR2; Quinone; Quinone reductase 2; Ribosyldihydronicotinamide dehydrogenase [quinone]; Ribosyldihydronicotinamide dehydrogenase
Target Background
This gene encodes a member of the thioredoxin family of enzymes. It is a cytosolic and ubiquitously expressed flavoprotein that catalyzes the two-electron reduction of quinone substrates and uses dihydronicotinamide riboside as a reducing coenzyme. Mutations in this gene have been associated with neurodegenerative diseases and several cancers. Alternative splicing results in multiple transcript variants.
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