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Rabbit anti-Human NRBP1 Polyclonal Antibody

The antibody against NRBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01402A

The antibody against NRBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01402A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRBP1
Target SynonymsMADM; NRBP; BCON3; MUDPNP; NRBP1FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesJurkat, MCF7, Mouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1).Target SpeciesHuman
Immunogen SequenceAFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSSUniprot IDQ9UHY1
Background Information
  • Uniprot Id

    Q9UHY1

  • Target Species

    Human

  • Target Name

    NRBP1

  • Target Full Name

    Nuclear receptor-binding protein

  • Target Function

    May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.

  • Target Subcellular Location

    Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.

  • Target Protein Families

    Protein kinase superfamily, Ser/Thr protein kinase family

  • Target Tissue Specificity

    Ubiquitously expressed in all tissues examined with high levels in the testis.

  • Target Synonyms

    BCON3; MADM; MUDPNP; Multiple domain putative nuclear protein; Myeloid leukemia factor 1 adaptor molecule; NRBP; NRBP_HUMAN; NRBP1; Nuclear receptor binding protein; Nuclear receptor-binding protein

  • Target Background

    Predicted to enable protein homodimerization activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endomembrane system.

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