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The antibody against NRBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NRBP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01402A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NRBP1 |
| Target Synonyms | MADM; NRBP; BCON3; MUDPNP; NRBP1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, MCF7, Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 406-535 of human NRBP1 (NP_037524.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | AFGLPRPQQPQQEEVTSPVVPPSVKTPTPEPAEVETRKVVLMQCNIESVEEGVKHHLTLLLKLEDKLNRHLSCDLMPNENIPELAAELVQLGFISEADQSRLTSLLEETLNKFNFARNSTLNSAAVTVSS | Uniprot ID | Q9UHY1 |
Uniprot Id
Q9UHY1
Target Species
Human
Target Name
NRBP1
Target Full Name
Nuclear receptor-binding protein
Target Function
May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases. Binding to the NS3 protein of dengue virus type 2 appears to subvert this activity into the alteration of the intracellular membrane structure associated with flaviviral replication.
Target Subcellular Location
Cytoplasm, cell cortex. Endomembrane system. Cell projection, lamellipodium. Note=Colocalizes with activated RAC3 to endomembranes and at the cell periphery in lamellipodia.
Target Protein Families
Protein kinase superfamily, Ser/Thr protein kinase family
Target Tissue Specificity
Ubiquitously expressed in all tissues examined with high levels in the testis.
Target Synonyms
BCON3; MADM; MUDPNP; Multiple domain putative nuclear protein; Myeloid leukemia factor 1 adaptor molecule; NRBP; NRBP_HUMAN; NRBP1; Nuclear receptor binding protein; Nuclear receptor-binding protein
Target Background
Predicted to enable protein homodimerization activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Located in endomembrane system.
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