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The antibody against NRP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Neuropilin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NRP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Neuropilin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of Jurkat cells using Neuropilin-2 Polyclonal Antibody
| Cat.No | ADC-33445A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NRP2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Neuropilin-2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60462 |
Uniprot Id
O60462
Target Species
Human
Target Name
NRP2
Target Full Name
Neuropilin-2
Target Function
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.; (Microbial infection) Acts as a receptor for human cytomegalovirus pentamer-dependent entry in epithelial and endothelial cells.
Target Subcellular Location
Membrane; Single-pass type I membrane protein.; [Isoform s9]: Secreted.
Target Protein Families
Neuropilin family
Target Synonyms
MGC126574; Neuropilin 2; Neuropilin-2; Neuropilin2; NP 2; NP2 ; NPN 2; NPN2; NRP 2; Nrp2; NRP2_HUMAN; PRO2714 ; Receptor for VEGF165 and semaphorins class3; Vascular endothelial cell growth factor 165 receptor 2; Vascular endothelial growth factor 165 receptor 2; VEGF1265R2; VEGF165R2
Target Background
This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. This protein has also been determined to act as a co-receptor for SARS-CoV-2 (which causes COVID-19) to infect host cells.
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