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The antibody against NRTN was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NTN. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against NRTN was raised in rabbit using the Synthesized peptide derived from the Internal region of Human NTN. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western Blot analysis of K562 cells using NTN Polyclonal Antibody
Western Blot analysis of K562 L929 cells using NTN Polyclonal Antibody2
| Cat.No | ADC-36735A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NRTN |
| Target Synonyms | Neurturin antibody; Neurturin precursor antibody; NRTN antibody; NRTN_HUMAN antibody; NTN antibody; prepro-neurturin antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human NTN. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99748 |
Uniprot Id
Q99748
Target Species
Human
Target Name
NRTN
Target Full Name
Neurturin
Target Function
Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.
Target Involvement
Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.
Target Subcellular Location
Secreted.
Target Protein Families
TGF-beta family, GDNF subfamily
Target Synonyms
Neurturin; Neurturin precursor; NRTN; NRTN_HUMAN; NTN; prepro-neurturin
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