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Rabbit anti-Human NRTN Polyclonal Antibody

The antibody against NRTN was raised in rabbit using the Human NRTN-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-51194A

The antibody against NRTN was raised in rabbit using the Human NRTN-Specific as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-51194A ClonalityPolyclonal
Host SpeciesRabbitTarget NameNRTN
Target SynonymsNeurturin antibody; Neurturin precursor antibody; NRTN antibody; NRTN_HUMAN antibody; NTN antibody; prepro-neurturin antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman NRTN-SpecificTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ99748
Background Information
  • Uniprot Id

    Q99748

  • Target Species

    Human

  • Target Name

    NRTN

  • Target Full Name

    Neurturin

  • Target Function

    Supports the survival of sympathetic neurons in culture. May regulate the development and maintenance of the CNS. Might control the size of non-neuronal cell population such as haemopoietic cells.

  • Target Involvement

    Genetic variations in NRTN may contribute to Hirschsprung disease, in association with mutations of RET gene, and possibly mutations in other loci. Hirschsprung disease is a disorder of neural crest development is characterized by the absence of intramural ganglion cells in the hindgut, often resulting in intestinal obstruction.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    TGF-beta family, GDNF subfamily

  • Target Synonyms

    Neurturin; Neurturin precursor; NRTN; NRTN_HUMAN; NTN; prepro-neurturin

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