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The antibody against NSL1 was raised in rabbit using the Recombinant Human Kinetochore-associated protein NSL1 homolog protein (225-272AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against NSL1 was raised in rabbit using the Recombinant Human Kinetochore-associated protein NSL1 homolog protein (225-272AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-02751A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NSL1 |
| Target Synonyms | homolog (S. cerevisiae) antibody; NSL1_HUMAN antibody, MIND kinetochore complex component | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Kinetochore-associated protein NSL1 homolog protein (225-272AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96IY1 |
Uniprot Id
Q96IY1
Target Species
Human
Target Name
NSL1
Target Full Name
Kinetochore-associated protein NSL1 homolog
Target Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and kinetochore formation during mitosis.
Target Subcellular Location
Nucleus. Chromosome, centromere, kinetochore. Note=Associated with the kinetochore (PubMed:15502821, PubMed:16585270).
Target Synonyms
4833432M17Rik; AI451597; C1orf48; DC31; DC8; DKFZp566O1646; Gm105; Gm984; Kinetochore associated protein NSL1 homolog; Kinetochore-associated protein NSL1 homolog; MIS14; NSL1; NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); NSL1_HUMAN
Target Background
This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene. There is a pseudogene of the 3' UTR region of this gene on chromosome X.
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