Rabbit anti-Human NSMF Polyclonal Antibody

The antibody against NSMF was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_001124443.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-03922A

Number

Cat.No	ADA-03922A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	NSMF
Target Synonyms	HH9; NELF; NSMF	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, BT-474, HT-29, LO2, Mouse brain	Application	ELISA, WB

Cat.No

ADA-03922A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

NSMF

Target Synonyms

HH9; NELF; NSMF

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, BT-474, HT-29, LO2, Mouse brain

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_001124443.1).	Target Species	Human
Uniprot ID	Q6X4W1	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 226-505 of human NSMF (NP_001124443.1).

Target Species

Human

Uniprot ID

Q6X4W1

Immunogen Sequence

Background Information

Uniprot Id

Q6X4W1
Target Species

Human
Target Name

NSMF
Target Full Name

NMDA receptor synaptonuclear signaling and neuronal migration factor
Target Function

Couples NMDA-sensitive glutamate receptor signaling to the nucleus and triggers long-lasting changes in the cytoarchitecture of dendrites and spine synapse processes. Part of the cAMP response element-binding protein (CREB) shut-off signaling pathway. Stimulates outgrowth of olfactory axons and migration of gonadotropin-releasing hormone (GnRH) and luteinizing-hormone-releasing hormone (LHRH) neuronal cells.
Target Involvement

Hypogonadotropic hypogonadism 9 with or without anosmia (HH9)
Target Subcellular Location

Nucleus. Nucleus envelope. Nucleus membrane. Nucleus matrix. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Cell projection, dendrite. Cell junction, synapse. Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic density. Membrane.
Target Protein Families

NSMF family
Target Tissue Specificity

Highly expressed in adult and fetal brain. Weakly expressed in heart, liver, spleen, testis, small intestine, skeletal muscle, peripheral white blood cells and kidney.
Target Synonyms

Nasal embryonic LHRH factor; Nasal embryonic luteinizing hormone releasing hormone factor; Nasal embryonic luteinizing hormone-releasing hormone factor; Nelf; NELF_HUMAN
Target Background

The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human NSMF Polyclonal Antibody

Specifications

Immunogen Information

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