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The antibody against NSUN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 26-290 of human NSUN4 (NP_950245.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against NSUN4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 26-290 of human NSUN4 (NP_950245.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05328A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NSUN4 |
| Target Synonyms | SHTAP; NSUN4 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, HepG2, HT-29, Mouse brain, Mouse testis, SH-SY5Y | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 26-290 of human NSUN4 (NP_950245.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q96CB9 | Immunogen Sequence |
Uniprot Id
Q96CB9
Target Species
Human
Target Name
NSUN4
Target Full Name
5-cytosine rRNA methyltransferase NSUN4
Target Function
Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.
Target Subcellular Location
Mitochondrion.
Target Protein Families
Class I-like SAM-binding methyltransferase superfamily, RsmB/NOP family
Target Synonyms
5 methylcytosine rRNA methyltransferase NSUN4; EC=2.1.1.-; NOL1/NOP2/Sun domain family member 4; NOL1/NOP2/Sun domain family, member 4; NOP2/Sun domain family, member 4; Nsun4; NSUN4_HUMAN; Putative methyltransferase NSUN4; RP4-603I14.2; Shtap; Sperm head and tail associated protein
Target Background
Enables rRNA (cytosine-C5-)-methyltransferase activity. Involved in rRNA methylation. Part of mitochondrial large ribosomal subunit.
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