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The antibody against NTF3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-257 of human NTF3 (NP_002518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against NTF3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 19-257 of human NTF3 (NP_002518.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-04164A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NTF3 |
| Target Synonyms | NT3; HDNF; NGF2; NT-3; NGF-2; NTF3 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 19-257 of human NTF3 (NP_002518.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P20783 | Immunogen Sequence |
Uniprot Id
P20783
Target Species
Human
Target Name
NTF3
Target Full Name
Neurotrophin-3
Target Function
Seems to promote the survival of visceral and proprioceptive sensory neurons.
Target Subcellular Location
Secreted.
Target Protein Families
NGF-beta family
Target Tissue Specificity
Brain and peripheral tissues.
Target Research Area
Neuroscience
Target Synonyms
HDNF; MGC129711; Nerve growth factor 2; Neurotrophic factor; Neurotrophin 3 precursor; Neurotrophin-3; Neurotrophin3; NGF 2; NGF-2; NGF2; NT 3; NT-3; NT3; NTF 3; NTF3; NTF3_HUMAN
Target Background
The protein encoded by this gene is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NTF3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat and mouse.
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